الفهرس 
Chronic Obstructive Pulmonary DiseaseOnly 14 pages are availabe for public view
 |  | from | 188 |  |  |
| | | from | 188 | | |
Abstract
SUMMARY
he present study is a prospective study conducted on 45
patients with acute exacerbation of chronic obstructive
pulmonary disease admitted in Respiratory Intensive Care
Unit in Abbassia Chest Hospital, all patients were diagnosed
(by clinical, radiological and arterial blood gases) as having
respiratory failure type II necessitating oxygen therapy.
The aim of the study is to evaluate the efficacy of
optiflow device in comparison to venturi mask.
The selected COPD patients were submitted to
1- Full history taking.
2- Clinical examination (general and local examination).
3- Routine laboratory investigation: Complete Blood
Picture, kidney function, liver function, random blood
sugar and Serum electrolytes).
4- Plain chest x-ray (postero- anterior view).
5- Electrocardiography (ECG)
6- Arterial blood gases.
The patients were classified into two groups:
1st Group: included twenty randomly selected COPD patients
in acute exacerbations connected to Venturi-mask.
2nd Group: included twenty-five randomly selected COPD
patients in acute exacerbations connected to nasal
high flow oxygen with optiflow system.
from the present study, the following results were obtained:
• Out of 45 cases with acute exacerbation of chronic obstructive
pulmonary disease 38 patients were males representing
(84.4%) and 7 females representing (15.6%) with mean age
(60.7+7) years in the 1st group and (60+5) years in 2nd group
with no significant difference in age and sex.
• No significant difference detected in co morbidities between
both groups.
• No statistically significant difference between the two groups
according to baseline ABG variables (on admission).
• In both methods (NHF & Venturi mask) ; There was
statistically significant improvement in arterial blood gases
(ABG) variables (as following: raised PH, PO2 and O2
saturation while PCO2 was declined) when compared to
baseline ABG.
• Although there was no significant difference in weaning results
between both groups, there was significant decline in PCO2
within NHF group.
• There was no significant difference in the outcome and the end
result between both groups; successful weaning was carried
out in 70% of venturi group and 64% of nasal high flow group
Summary
130
while failure was reported in 30% of the 1st group and 36% in
the 2nd group.
• There was significant difference between the two groups
in length of ICU stay where it was longer in the VM group (3.1
days ± 1.25) than the NHF group (1.52 days ± 1.1).
• There was no statistically significant difference in
complications between both groups.
• There was no significant correlation between changes in the
fraction of inspired oxygen FIO2 and flow of O2 of the
venture mask and the changes in blood gases. Also, there
was no significant correlation between changes in the fraction
of inspired oxygen FIO2 and flow of O2 of NHF and the
changes in blood gases.