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Abstract Recent randomized trials justify the routine use of HF for adjuvant radiotherapy in women with breast cancer. Postmastectomy radiotherapy still an open area for extensive research, our study showed that hypofractionated radiation therapy is comparable to that of CF without evidence of inferior local tumor control or higher adverse effects. Hypofractionated radiation therapy can be recommended as safe and effective alternatives to CF for postmastectomy chest wall radiotherapy. These results need to be evaluated with multicenter larger sample size. |