الفهرس | Only 14 pages are availabe for public view |
Abstract Summary This study was conducted prospectively on 53 patients with unexplained pleural effusion at Abbassia chest hospital during the period from December 2013 to August 2014. This study included 33 males & 20 females, with a mean±SD age 56.83 ± 11.47 year. Chest ultrasound was done to every patient prior to the procedure ( thoracoscope, open pleural biopsy or Abrams needle) to detect the sonographic findings as regard pleural effusion, loculation, fibrin strands, and underlying lung lesions. Also chest CT was done to every patient with exudative pleural effusion prior to the procedure to examine the concordance and discordance between it and chest ultrasound as regard pleural effusion, loculation, fibrin strands, and underlying lung lesions. Imaging findings were correlated with operative findings. from the present study, the following results were obtained: Our study showd that there were highly significant differences between malignant and non-malignant groups as regards the nature of effusion; anechoic pattern was associated with transudative effusion (100%), complex septated pattern was associated with malignant effusion (47.6%) and complex non septated pattern was associated with non malignant effusion (45%) but there were no any nature limited to any type. In the present study, US altered patient diagnostic process either thorough specifying a definite diagnosis, adding new findings, confirmed a provisional diagnosis or excluding differential diagnosis in an appreciable number of patients. For example, replacing medical thoracoscopy with open pleural biopsy due to presence of thick fibrous septation and multiloculations. Our study showed that pleural thickening and nodularities were highly significantly associated with malignant effusion (61.9% and 66.7%). There were high variability between size and type of effusion. In malignant effusion there were 16/21 (75% massive effusion, 6/21 moderate effusion (29%) and 0/21 (0%) mild effusions.In non malignant effusion there were 7/32 (22%) massive effusion,16/32 (50%) moderate effusion and 11/32 (34%) mild effusion. The results of our study showed that there is concordance between chest ultrasound and chest CT in detection of 53/53 patients (100%) with pleural effusion, 1/1 patient (100%) with underlying mass, 14/14 patients (100%) with pleural thickening more than 1 cm with diaphragmatic pleural nodules. The results of this study showed that chest CT was unable to detect internal echogenicity of pleural effusion as compared with chest ultrasound, which was able to detect four sonographic patterns of internal echogenicity of pleural effusion. Pleural effusion was anechoic in 15/53 patients, complex non-septated in 18/53 patients, complex septated in 19/53 patients, and homogeneously echogenic in 1/53 patient. The homogenously echogenic pattern was seen in hemorrhagic effusion. The results of this study showed that chest ultrasound was superior to chest CT in detection of 19/19 patients (100%) with fibrin strands and multiloculation. 12/19 patients showed thick fibrous septation and multiloculation whereas 7/19 cases showed few fibrin strands. These findings were detected by ultrasound consistent with the operative findings but not detected by chest CT in any of them. Computed tomography is still considered the gold standard for detection of pleural effusions. In addition, it enables evaluation of the pleural space, allows accurate and detailed evaluation of the thoracic wall, lung parenchyma, and mediastinum. Ultrasound had the best sensitivity and specificity and other test parameters in diagnosing pleural effusion as compared to chest X-ray. Ultrasound had a significant better pleural effusion sensitivity, specificity, PPV, NPV, and accuracy than those of X-ray. |