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Abstract This study was aiming at detection of percentage of microcytic hypochromic anemia in comparison to other types of anemia in infants and children (6 months-2 years) It included 100 pale infants and were divided into Group I: (70 infants with MHA) and group II: (30 infants with other types of anemia). Group I was subdivided into group Ia (patients with iron deficiency anemia) and group Ib patients with ( thalassaemia). Thorough history taking and complete clinical examination were done for studied patients in additional to Hb level, MCV, MCHC and reticulocytic count. For patients with MHA, serum iron study and Hb electropheresis were done Our results showed that there were no significant differences between group I and group II regarding clinical findings including: temperature, respiratory rate, heart rate, weight, length and head circumference. There were significant differences between group I and group II regarding hemoglobin level where in group I it is higher than in group II (P<0.0001). Reticulocytic count, Mean corpuscular volume and Mean corpuscular hemoglobin concentration were significantly higher in group II than in group I (P<0.001 for each). There were highly significant differences between group Ia and group Ib regarding serum iron, serum ferritin and total iron binding capacity (p< 0.001, 0.001 and 0.012 respectively). Some clinical data in both groups include pallor( 100% in both groups), jaundice ( 2.9% in group I and 0% in group II) , organomegly( 11.4% in group I and 0% in group II) , positive family history( 2.9% in group I and 0% in group II) and parasitic infestation( 41.5% in group I and 0% in group II). |