الفهرس 
ACUTE CORONARY SYNDROMEOnly 14 pages are availabe for public view
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Abstract
Acute coronary syndrome includes acute myocardial infarction (resulting in ST elevation or non-ST elevation) and unstable angina. Recognizing a patient with ACS is important for prognosis and management. ACS remains to be the leading cause of morbidity and mortality and it is one of the most difficult challenges to be faced in emergency department. The earliest ways to diagnose AMI in patients with chest pain was frequent electrocardiography(ECG) and blood collection to measure biochemical cardiac markers; cardiac troponin and CK-MB. Cardiac troponin I levels start to rise 3 to 12 hours after the onset of ischemia, peak at 12 to 24 hours, and may remain elevated for 7 to 14 days. Elevated troponin levels correlate with pathologically proven myocardial necrosis and indicate poor prognosis in patients with suspected ACS. Elevated serum cTn concentrations denote an increased long-term risk of cardiovascular events and mortality. So this study was created to evaluate and validate the cut - off values for troponin I in diagnosing and prediction the risk of mortality in patients with acute coronary syndrome in the emergency department. The study included 100 patients admitted to emergency department suffering from typical chest pain and/or shortness of breath, diagnosed as having ACS. Data were collected from ER included: serial 12 lead ECG, echocardiography for exclusion of pulmonary embolism, cardiomyopathy and aortic dissection. Routine laboratory investigations including lipid profile, blood glucose level and kidney and liver function tests. Troponin I and CK-MB were collected at (0-3 hours, 6-9 hours and 12-24 hours)and evaluation of the relation between troponin I levels and mortality at 40 days.