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Abstract The basal ganglia, as a group of nuclei in the interior of the brain, have extensive connections with almost all regions of the brain with two main connecting circuits related to the caudate nucleus ”the cognitive loop• and the putamen ”the motor loop” (Williams et al., 1989). They were thought to be only involved in the initiation and control of movement, but it now seems clear that, they are also involved in a number of neuropsychiatric symptoms including psychosis, depression and dementia (Kaplan & Sadock, 1991). Recently the relations of several neuropsychiatric disorders to dysfunctions of the basal ganglia became more clear through the introduction of the neuroimaging techniques which were not otherwise available and so, more detailed structural and functional changes could be detected. The commonest neuropsychiatric disorders involved are, Parkinsonism, schizophrenia, mood disorders, obsessive compulsive disorder, generalized anxiety disorder, Tourette’ s syndrome, Huntington’s disease, Wilson 1 s disease 1 tardive movement syndromes and dystonic syndromes. |