![]() | Only 14 pages are availabe for public view |
Abstract The oxidative stress of enrofloxacin administration and the protective effect of green tea extract on the oxidative stress were investigated. Ninety white male albino rats, 12-16 weeks old and average body weight 140-190 gm. Rats were housed separately in metal cages under the same constant environmental and nutritional condition through the period of investigation. All rats were randomly divided into 6 main equal groups, 15 animals each, placed in individual cages and classified as follow: Group I (Control normal group): Comprised 15 male rats, not received any type of treatments Group II (green tea extract 2%): comprised 15 male rats, received no drugs, with replacement of drinking water with green tea extract 2%. Group III (green tea extract 5%): comprised 15 male rats, received no drugs, with replacement of drinking water with green tea extract 5%. Group IV (enrofloxacin): comprised 15 male rats, received an intraperitoneal dose of enrofloxacin equals 75 mg/kg Bwt. Group V (EFX + GTE 2%): comprised 15 male rats, received an intraperitoneal dose of enrofloxacin equals 75 mg/kg Bwt with green tea extract 2% in drinking water. Group VI (EFX + GTE 5%): comprised 15 male rats, received an intraperitoneal dose of enrofloxacin equals 75 mg/kg Bwt with green tea extract 5% in drinking water. |