الفهرس 
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Abstract
Evaluation Of The Relation Between Factor V Leiden,
Prothrombin Gene Mutation And Recurrent pregnancy loss
Recurrent pregnancy loss is defined as two or three consecutive pregnancy losses, causes of RPL includes genetic, uterine, hormonal and immunological, now inherited thrombophilia is suggested as a possible cause of RPL. Thrombophilia is defined as increased tendency of blood to clot increasing risk for thrombosis . The aim of the study was to evaluate the role of FVL , prothrombin gene mutation the most common mutations responsible for inherited thrombophilia in RPL, this will allow couples at high risk for RPL due to these two mutations to receive proper genetic counseling ,treatment and improve pregnancy outcome.
the study was carried out on 56 cases had at least two consecutive losses
after exclusion of all known causes of RPL and control group of 48 women
had at least one child without any complications in pregnancy, there was
increased prevalence of both mutations in cases than control but to a non
significant level, a statistically significant increase was reported in cases
had abortion in second trimester compared to cases had abortion in first
trimester.