الفهرس | Only 14 pages are availabe for public view |
Abstract The chronic lymphoproliferative disorders are a heterogeneous group of diseases that are clonal expansions of malignantly transformed cells whose differentiation has been interrupted and arrested early in lymphocyte ontogeny. The diagnostic approach in these disorders has changed dramatically in recent years. Technological advances uncovered new complexities and made in possible to firmly and clearly establish the lineage and stage of differentiation. Although morphology, cytochemistry and cytogenetics may play an important role in the diagnosis of lymphoproliferative disoders, immunophenotyping assumes a much more important |