الفهرس 
1-LiveOnly 14 pages are availabe for public view
 |  | from | 35 |  |  |
| | | from | 35 | | |
Abstract
This study aimed to Investigate the effect of phytochemicals in artichoke ( Cynara scolymus, L. ) on liver damage initiated by carbon tetrachloride (Ccl4) . Forty five adult male albino rats, weighting 160-170g were divided into nine groups each with five rats . One of them was kept as a Control (–ve) Group, while the other eight groups were injected by carbon tetrachloride, The different parts of artichoke plant were added at a percent 7.5% from the basel diet and given as a single either or a raw or cooked mixture(all parts)( roots ,stems, bracts, leaves& receptacle). Glutamic oxaloacetic transaminase (G.O.T), glutamic pyruvic transaminase (G.P.T), and alkaline phosphatase (A.L.P) , total bilirubin, direct bilirubin, indirect bilirubin, albumin, ,total protein, superoxide dismutase(SOD), glutathione peroxidase(GPX), catalase(CAT), lipid profile cholesterol, tri- glycerides (T.G), high density lipoprotein cholesterol (H.D.L-c), low density lipoprotein cholesterol (L.D.L-c), very low density lipoprotein cholesterol (V.L.D.L-c), atherogenic index(A.I), urea, creatinine, uric acid assayed and histopatholigical changes were examined . from the obtained results it could be concoluded that artichoke plant parts enhanced the liver functions. The best BWG% was recorded for hepatic rats fed on artichoke roots (7.5%). artichoke bracts(7.5%) caused an enhancement of liver functions, lowering GOT and GPT enzymes. As regards to serum SOD, catalase (CAT) or GPX, the best treatments are considered artichoke bracts or stems and receptacles(7.5%), respectively. Histopathological investigation confirmed the biochemical changes in general the liver functions .