الفهرس | Only 14 pages are availabe for public view |
Abstract Chronic hepatitis C virus (HCV) infection is a major worldwide public health problem. Egypt has the highest prevalence of adult HCV infection in the world, average 18%-22% in rural areas. Hepatitis C virus (HCV) is a major cause of hepatic disease and of liver transplantation worldwide. Mannan-binding lectin (MBL) is a liver-derived pluripotent serum lectin that plays a role in the innate immune system of the host. It is an acute-phase protein that is involved in the activation of the classical complement pathway. MBL may play a defensive role in HCV infection. This study was designed to detect relation between serum level of MBL and grades of liver fibrosis in chronic HCV patients. And to detect also the impact of serum level of MBL on early virological response. |