الفهرس 
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Abstract
Pediatric non Hodgkin lymphoma NHL is a diverse collection of malignant neoplasm derived from mature and immature lymphoid cells of either B-cell or T-cell origin. The majority of cases with T-cell lymphoblastic lymphoma (T-LL) present with rapidly enlarged lymph node, mediastinal mass, symptoms of SVC obstruction or spinal cord compression. Precursor B-cell LL tends to have limited disease in sites including skin, bones and lymph nodes. St. Jude staging system for NHL has been widely accepted for staging. Treatment of LL has evolved over time from conventional highgrade NHL schedules to ALL- derived protocols. Patients and methods: A retrospective review of patients‘ charts with proved diagnosis of Lymphoblastic Lymphoma diagnosed and treated at National Cancer Institute of Egypt during the period from 1st of January 2006 to 31st of December 2012 was done. Results: The study included 20 patients, they were 17 males (85%) and 3 females (15%).Mean age at diagnosis was 7.6 years old. Two patients (2/20) (10%) were diagnosed as BLL while eighteen patients (18/20) (90%) were diagnosed with TLL. As for the tumor primary site: Mediastinal mass was the most common primary site observed in 12 patients (60%). BM involvement was observed in 8 patients (40%). Four (20%) of the studied patients experienced disease RL/PD. Patients with high LDH> 1000 IU has lower overall survival compared with patients with lower LDH <1000 at initial presentation. The study was started with 20 cases, of which 11 patients (55%) are still alive and 9 (45%) are dead, with overall survival (54%). Conclusion: Treatment related mortality including infections and non adherence to treatment resulted in decreased overall survival and outcome in patients with lymphoblastic lymphoma. Recommendation: Control of infections and more adherence are required to obtain better outcomes in those patients as other studies achieved almost 90-95% overall survival in lymphoblastic lymphoma patients which is due to keeping a firm grip on the infectious process and better patient-doctor communication for better understanding of importance of adherence to treatment and its effect on survival. Keywords: Lymphoblastic lymphoma / Cancer / Pediatric / outcome.