الفهرس 
Pathophysiology of PTCAOnly 14 pages are availabe for public view
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Abstract
Background: As Coronary angioplasty balloons interact directly with
vascular endothelium, the lesion morphology has been an important
predictor of outcome of PTCA.
Aim of the work: This study aimed to study the effect of
morphological characteristics of coronary lesion on early outcome of
PTCA.
Patients & Methods: A total number of 66 coronary lesions in 50
patients were studied. We looked for different lesion morphological
characteristics individually to assess the impact of each character on
PTCA result. To make a global assessment of coronary lesion., A new
angiographic score had been proposed, taking in consideration the effect
of different morphological characters. Anatomical success was
evaluated by dobutarnine echocardiography.
Results: The length of coronary lesion, tortuosity, contour and caliber
of coronary artery containing lesion were significant morphological
predictor of optimal early results (P<O.OS). There was highly significant
relation between angiographic score and early results of PTCA.
(P<O.OOl). Optimal success was 100%, 82.97% and 11.11% with
angiographic score< 13, -13-15 and)l5 respectively.
Functional evaluation outcome of PTCA was done using
dobutarnine echocardiography (D.E). It was performed within one week
(90% of cases in the next day of PTCA). There was significant
improvement of basic WMSI after PTCA (from 1.13 ± 0.21 to 1.09 ±
1.18) and in WMSI with dobutamine infusion in 96.7% of patients with
optimal results (from 1.09 ± 1.18 to 1.05 ± 0.14). No major side effects
were reported.
Conclusion: The proposed angiographic score seemed to be valuable in
predicting outcome of PTCA. The length of lesion, tortuosity, contour
and caliber of coronary artery are predictor of outcome of PTCA.
Dobutarnine echocardiography is a valuable safe method to evaluate
patients after coronary angioplasty.