الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The prevalence of quinoline and pyrazole moieties as biologically active molecules highlighted the importance of these heterocyclic ring systems in medicinal chemistry and stimulated the need for elegant and efficient ways to make use of these heterocyclic functions.
Quinoline and pyrazole containing compounds have a long history of application as pharmaceutical agents having anti-inflammatory, analgesic, antimicrobial, antitumor, antiviral, antimalarial and antiparasitic activities.
This motivated our interest in the present investigation to design and synthesize new compounds comprising quinoline and pyrazole moieties. All the new compounds were tested for their antibacterial and antifungal activities while some of the synthesized compounds were selected to be screened for their anti-inflammatory activity. Biological screening results revealed some encouraging results when compared to the applied standards.
The work done in the present thesis can be classified as follows:
Chapter 1:
Introduction:
This chapter presented a brief literature survey on some biologically active quinoline and pyrazole isolated or combined compounds exhibiting anti-inflammatory, antimicrobial activities as well as antiparasitic, antitubercular, antiviral and cytotoxic activities.
Chapter 2:
Research objectives:
This chapter demonstrated the rationale upon which the synthesis of the new dual acting anti-inflammatory, antimicrobial compounds was designed.
Chapter 3:
Discussion:
This section presented the theories upon which new compounds were synthesized based on methods previously reported in the literature. The structures of the new synthesized compounds were confirmed by microanalytical and spectral data.