الفهرس 
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Abstract
The present study aimed at evaluating the efficacy of hormonal intervention with gonadotropic releasing hormone (Gn-RH), anti-prolactin (Bromocriptine) or calcium preparation administration on the reproductive performance and fertility traits of lactating she-rabbit. For this purpose, New Zealand White (pluriparous does (n=120) and fertile bucks (n=5)). Does were assigned into four comparable groups as follows:
- First (n=30) was received orally tablets of 100 mg/kg calcium citrate.
- Second (n=30) was injected intramuscularly by 0.2ml (0.84ug) of GnRH analogue (buserline acetate, Recpetal®, Intervet, The Netherlands).
- Third (n=30) was administered orally 2.5mg/head of the anti-prolactin hormone (Bromocriptine, Parlodel®, Sandoz, Basel, Switzerland).
- Fourth (n= 30) was left without treatment as control. At the 11th day of parturition, the treatment was started for all groups.
After 2 hours of treatment, all does were naturally mated by well proven bucks. after 2, 4, 6 and 8 hours, vaginal smears were collected, prepared and stained with Giemsa for vaginal mucosal cells (parabasal, intermediate, superficial and anuclear) and after 12 hours, blood serum samples were taken for assay of progesterone..
Does were checked for pregnancy by abdominal palpation 15 days post-breeding. After 4-5 hours of kidding, the litter size and weight were determined per each doe.
At the end of the experiment, a total number of 36 does were retreated by GnRh (n=12), calcium citrate (n=12) and bromocriptine (n=12) in addition to 12 does were remained without treatment as control. A total of three does in each group were sacrificed at 2,4,6,8 hrs post treatment. Ovaries from sacrificed does were collected histological examination.
After statistical analysis of the obtained data, results revealed:
1- Effect of Gn-RH, anti-prolactin (bromocriptine) and calcium on the ovarian biometry. 2- Effect of Gn-RH, anti-prolactin (bromocriptine) and calcium on the ovarian morphology:
• Gn-RH enhanced follicular population but at mild degree and also some follicles showed cystic formation at 8 hours post-treatment.
• Anti-prolactin group showed a moderate increase in the number of follicles incorporated with moderate follicular degeneration and cystic formation at 6 hours post-treatment.
• Luteinization of stromal cells was high in calcium and GnRH groups and moderate after anti-prolactin treatment.
• Calcium increased the number of follicles at different stages of growth at 4 hours post-treatment, though some showed cystic formation at 8 hours post-treatment.
3- Effect of GnRH, anti-prolactin (bromocriptine) and calcium on the predominant vaginal cell type
4- Effect of GnRH, anti-prolactin (bromocriptine) and calcium on the serum progesterone concentration. 5- Effect of GnRH, anti-prolactin (bromocriptine) and calcium on the fertility traits.