Search In this Thesis
   Search In this Thesis  
العنوان
Physiological Studies On The Effect Of Myostatin Gene And Its InhibitorsOn Muscle Growth And Function In Egyptian Buffaloes /
المؤلف
Alwakeel, Rasha Alsaeed Atia Mohammed,
هيئة الاعداد
باحث / رشا السعيد عطية محمد الوكيل
مشرف / ميشيل فهمي سعد
مشرف / شوقي عبد الهادي محمود
مشرف / محمد السيد رزق
الموضوع
Veterinary medicine.
تاريخ النشر
2014.
عدد الصفحات
111 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
20/2/2014
مكان الإجازة
جامعة كفر الشيخ - كلية الطب البيطري - قسم الفسيولوجيا
الفهرس
Only 14 pages are availabe for public view

from 111

from 111

Abstract

Using the traditional selection does not solve the problem of meat shortage in our country and with advent of molecular genetics and biotechnology, it becomes possible to significantly improve the meat production of animals. In this Study, blood and muscle tissue samples from Egyptian buffaloes were collected and then DNA and RNA were extracted also Serum samples from these animals were used for spectrophotometric measurement of Ca and P levels as well as ALP and GOT enzyme activities. The present study is the first report on polymorphisms of Mstn gene in Egyptian buffaloes and on the correlation between their SNPs with growth traits, MstnPro and mineral (Ca and P) and enzymatic (ALP and GOT) activity in serum of meat producing Egyptian buffaloes. The synonymous A31G was significantly (P ≤ 0.001) correlated with ADG, GH mRNA levels (at 24 month of age), MstnPro mRNA levels (at 6, 12 and 24 month of age), Ca, P , ALP and GOT serum levels (at 2 year of age). The GG animals have a higher ADG, GH, MstnPro, Ca, P , ALP and GOT as compared to AA genotype animals with lower meat production. This study may be practical for the improvement of Egyptian native buffaloes.