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العنوان
Association of elevated free fatty acids during late pregnancy with preterm delivery/
المؤلف
Fathy, Marwa Abdel Hamid.
هيئة الاعداد
باحث / مــــروة عبــد الحميـــد فتحـــــى
مناقش / هشام مصطفى جلال
مناقش / طارق عبد الظاهر قرقور
مشرف / السيد البدوى محمد عوض
الموضوع
Obstetrics. Gynecology.
تاريخ النشر
2014.
عدد الصفحات
30 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
23/1/2014
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Preterm delivery is defined as births occurring prior to 37 completed weeks, gestation. It complicates 12-13 % of all births in the United States.
Preterm delivery is not only a leading cause of neonatal morbidity and mortality. Its long-term squeals pose a serious problem for the offspring and for the mother. There is increased insulin resistance in children born preterm which may be a risk factor for the development of type 2 diabetes mellitus. Recently, the delivery of a preterm infant has been linked to increased cardiovascular morbidity and mortality for the mother later in life.
Elevated fasting plasma FFA levels at 30 weeks of gestation were associated with an increased risk of preterm delivery. This effect was independent of prepregnant obesity and several other known risk factors for preterm delivery, including cigarette smoking, ethnicity, and prior preterm delivery and a controlled trial found that fish oil (Omega-3) consumption during pregnancy increased its duration by 2–3 d.
So, the aim of our work was to demonstrate the influence of elevated serum maternal FFA during the third trimester on the risk of preterm delivery and demonstrating the effect of Omega-3 supplement.
The work was carried out on 90 healthy pregnant women who attended EL-Shatby Maternity University Hospital, after taking their consent, their age ranged between 20-30 years , their prepregnant body mass index (BMI) ≤ 29, 9 ≥ 20.20 and their gestational age was between (26 to 37 weeks).Women with serious obstetrical and nonobstetrical problems were excluded from participation.
To all subjects the following was carried out ;complete history taking, clinical examination, body mass index (BMI) was computed on self-reported pregravid weight and measured height at entry to antenatal care measured by (kg∕m2), participants were selected with a BMI ≤ 29.9 kg∕m2,gestational duration was calculated based upon the date of last regular menstrual Period confirmed or modified by abdominal ultrasound that included measuring Biparietal diameter – femur length (BPP-FL),fasting plasma FFAS were measured during the late 2nd and early 3rd trimester (26-30weeks of gestation).