الفهرس | Only 14 pages are availabe for public view |
Abstract Treatment of ethyl cyano hydrazide with arylidine malononitrile give amino pyridine.The latter react with different aldhydes,acids give 1,2,4- triazolopyridine. Also amino pyridine were allowed to react with different sugars afforded different glycosides. While reaction of arylidine malononitrile with thiourea in presence of ethanol and K2CO3 at reflux temperature afforded amino-5- isocyanothiopyrimidine. Amino -5-isocyanopyrimidine react with HCl in presence of ACOH or Formamide give fused pyrimidine derivatives. The synthesized compounds were tested for their biological activity as anti-bacterial and antiviral activity. |