الفهرس 
Alveolar boneOnly 14 pages are availabe for public view
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Abstract
Alveolar bone resorption is a serious consequence of persistent bacterial infection that may lead to tooth loss. Lipopolysaccharide (LPS) is a major constituent of the outer membrane of Gram-negative bacteria and one of the main virulence factors causing bone destruction. Objective:The aim of the current study was to investigate the effect of LPS on rat alveolar bone and to examine the possible antagonizing effect of omega-3 or vitamin C on LPS-induced alveolar bone changes. Methods: Ninety adult male albino rats were used and divided equally into two groups. The control group was subdivided into three subgroups: control saline group,control omega-3 group, control vitamin C group. The experimental group was subdivided into three subgroups: LPS group injected with LPS four times (1mg/ kg each 4 days) into the maxillary alveolar mucosa opposite the left first molar region, LPS+ omega-3 group injected with LPS and orally treated with omega-3 (1g/ kg body weight / day), LPS+ vitamin C group injected with LPS and orally treated with vitamin C (200 mg / kg body weight / day). At the end of the experimental period (21 days), rats were sacrificed and the left maxillary bone was resected and prepared for examination by light microscope, scanning electron microscope and elemental analysis.