الفهرس | Only 14 pages are availabe for public view |
Abstract Bacterial vaginosis is an imbalance of the normal vaginal flora with an overgrowth of anaerobic bacteria and a lack of the normal lactobacillary flora. Bacterial vaginosis during pregnancy has been associated with poor perinatal outcome and, in particular, preterm birth (PTB). Identification and treatment may reduce the risk of PTB and its consequences (McDonald et al., 2007). Vaginal symptoms such as abnormal discharge, unpleasant odor, itching, and burning typically lead to a diagnosis of bacterial vaginosis (BV), BV is the most common finding in women with vaginal symptoms, affecting 22% to 50% of symptomatic women (ACOG, 2006). Identifying the cause of vaginosis/vaginitis is essential for selection of pathogen-specific therapy. Clinicians have traditionally diagnosed vaginal infection using a combination of gynecologic examination, vaginal pH, microscopic evaluation of Gram stain and/or wet mount, and an amine odor test (Brown et al., 2004). Pregnancy with bacterial vaginosis is a higher risk of preterm delivery (Klebanoff et al., 2005). A significant association between bacterial vaginosis and pregnancy outcome has documented (Brunella Guerra., et al., 2006). The present study was done in Obstetrics & Gynecology department, Benha faculty of medicine, Benha university, Egypt-and in Obstetrics & Gynecology department, Elmabara Hospital, Tanta-Egypt The present study included 100 pregnant women, prior to 10 weeks of gestation, with history of previous preterm delivery (25-37weeks ) with the aim of investigating the relation between pregnancy outcome and early detection of bacterial vaginosis (BV). In the present study, the mean age of the studied case was 25 years. The prevalence of bacterial vaginosis was highest in age group between 20-30 year’s old and lowest in age group <20 years old. The result show no statistical significance (p>0.05). The prevalence of BV was higher in patient had a history of abortion than in women who did not report such history. In the present study, the highest prevalence of bacterial vaginosis +ve cases was in the group of female who had history of more than two previous deliveries. in the present study, the prevalence of BV in women who had history of previous abortion (80%) 25cases from 30 cases was higher than other women without history of previous abortion. In the present study bacterial vaginasis is associated with miscarriage in study group (13%).4 cases from 30 case In the present study bacterial vaginosis is associated with premature rupture of membrane in 6% of bacterial vaginosis +ve cases and in 3% of bacterial vaginosis +ve cases In the present study preterm labor occurred in 10/30 cases (33%) of bacterial vaginosis +ve cases In the present study bacterial vaginosis +ve caeses is associated with increase in neonatal sepsis incidence rate 10 % than in bacterial vaginosis –ve cases 5.7 %. In the present study bacterial vaginosis +ve caeses is associated with increase in neonatal Jaundice incidence rate 53% than in bacterial vaginosis –ve cases 52%. In the present study mean gestational age at birth in bacterial vaginosis +ve cases was 36 weeks, and in bacterial vaginosis –ve cases was 37 weeks In the present study Mean birth weight at birth in bacterial vaginosis +ve cases was2800 g, and in bacterial vaginosis –ve cases was 2850 g In the present study Apgar score after 5minutes in bacterial vaginosis +ve cases was 7, and in bacterial vaginosis –ve cases was 8. |