الفهرس | Only 14 pages are availabe for public view |
Abstract Acute stroke can lead to major disability and even death in some patients. MRI is an efficient examination that can rapidly diagnose stroke and therefore provide better management for the patient. The goal of (MRI) examination of patients presenting with neurological manifestations suggestive of cerebrovascular stroke as hemiplegia , numbness, disturbed level of consciousness ,ataxia and blurring of vision is to define the site, side (right or left),size ,age of the infarction and most important to give a definite diagnosis of acute stroke. Our study was conducted on (30) patients. 21 males and 9 females, with an age range between 44 and 65 years. They presented with one or more of the neurological manifestations suggestive of cerebrovascular stroke 2 to 50 hours from the onset of symptoms. They underwent MRI examination of the brain using the following sequences: (T1WI ,T2WI , FLAIR and DWI) ADC map was added in 10 patients. Any signal intensity abnormality (hyper , hypo or isointense) seen in the deferent sequences was then compared to the final clinical diagnosis. The male to female ratio was 7:3, which showed that males were more subject to acute stroke probably due to over stress, smoking and peripheral vascular disease. DWI showed great superiority in detecting acute ischemic lesions than T1WI, T2WI and FLAIR. DWI and ADC map were found useful imaging in detecting ischemic lesions at different stages. In the hyper acute stage i.e 6 hours of the onset of the stroke , the ischemic lesions appeared hyper intense on DWI and hypo intense on ADC map. In the acute stage i.e 6 hours to 3 days after onset of stroke, the picture was the same. On the other hand, FLAIR was superior to T1WI and T2WI in acute stroke. Conventional T1&T2WI detected infarctions in 19/30 patients (63%), FLAIR detected infarctions in 25/30 patients (83%). DWI picked the lesions in all 30 patients(100%). All the patients who did ADC map showed hypointense lesions(100%). DWI is able to depict areas of acute brain ischemia using the random motion of water molecules within living tissues, in the first few minutes of vascular occlusion during an ischemic stroke. Lesion can be rapidly detected as a hyperintense lesion on DWI within minutes of vessel occlusion and the onset of ischemia. The motion of water molecules in diffusion decrease in ischemic brain tissue which can be measured quantitatively with the apparent diffusion coefficient (ADC). DWI is the imaging modality of choice for the timely and accurate diagnosis of acute stroke. |