الفهرس 
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Abstract
Staphylococcus aureus is recognized worldwide as an important pathogen. These bacteria have a great versatility in their ability to colonize different hosts and cause infections at different anatomic sites owing to its production of wide variety of biologically active proteins. S. aureus has a capacity to produce a large number of potential virulence factors, including a variety of exotoxins and cell surface-associated proteins. One of the major surface proteins is staphylococcal protein A (Spa), which bacterial cell wall product that binds immunoglobulin G and impairs opsonisation by serum complement and phagocytosis by polymorphonuclear leukocytes.
Therefore, this work planned to explain the extraordinary pathogenic potential of this organism by identification and characterization of’ cell wall proteins of S. aureus mainly staphylococcal protein A (Spa).
A total number of 117 samples were collected from different sources; 66 milk samples, 15 chicken samples, 36 pus samples to detect the incidence of Staphylococcus aureus.
The higher prevalence of S. aureus were isolated from milk samples followed by chicken samples 45.83% , 33.30%
.