الفهرس 
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Abstract
This study highlights that fine needle aspiration cytology (FNAC) combined with flow cytometry (FCM) can reliably distinguish between reactive and neoplastic B-cell lymphoid populations and also subclassify lymphomas. In 93.75% of cases, an accurate diagnosis of reactive hyperplasia and non Hodgkin lymphoma (NHL) was made, three cases (6%) were false negative and no false positive was diagnosed. An accuracy rate of 90.9% was achieved in this study regarding the diagnosis of low grade B-NHLs. FCM was particularly helpful in subclassification of low grade B-NHLs which were difficult to differentiate by cytomorphology alone.
FCM immunophenotyping was not very informative in large B cell lymphomas. FCM is also likely to miss difficult cases such as anaplastic large cell lymphoma. In these cases cytomorphologic features are helpful in diagnosis of NHL. Inadequate and suspicious results by FNAC/FCM accounted for 3.3% and 14.3%, respectively. Scant cellularity, necrosis and excessive blood contamination were the most frequent causes of inadequate cases.