الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Plantar warts are benign epithelial proliferations on the sole of the foot most frequent over pressure points.
Plantar warts are caused by Human Papilloma Virus (HPV), a small non- enveloped double stranded DNA virus.
The treatment of patients with plantar warts continues to be a frustrating matter for both primary care physicians and dermatologists. They are usually treated by a wide variety of methods including cryotherapy, surgical excision, topically applied salicylic acid, bleomycin and lasers. The most commonly prescribed treatments for plantar warts are cryotherapy with liquid nitrogen and topical salicylic acid. Each mode of therapy has its own complications and failure rates.
Previous mentioned methods are not always successful and may be associated with adverse effects. Even when existing warts are successfully eradicated, patients may develop new warts in other areas.
The aim of this work is to compare topical salicylic acid ,cryosurgery using liquid nitrogen and CO2 laser in treatment of plantar warts.
We performed our study on 60 patients with plantar warts. The patients were subdivided randomly into 3 groups, each group composed of 20 patients. Group A was subjected to self treatment with 50% salicylic acid. The treatment was repeated daily for a maximum of eight weeks. Group B was treated with cryosurgery using liquid nitrogen; the liquid nitrogen was applied with a spray once weekly. The last 20 patients (group C) were treated with CO2 laser using intralesional anesthesia with lidocaine 2
%. All the patients were followed up for 12 weeks.
Our study showed that:
- There were no statistical significant differences between the three studied
groups regarding age and sex.
- There were no statistical significant differences between the three studied groups regarding number of warts per patient and type of warts.
- Group A and B have PW size statistically larger than group C, there were statistical significant differences between the three studied groups.
- As regard the time till clearance, group A and B have duration statistically longer than group C, there were statistical significant differences between the three studied groups.
- Partial clearance were found in 3 (15.0%), 4 (20.0%) and 4 (20.0%), complete clearance were found in 10 (50.0%), 12 (60.0%) and 16 (80.0%) for group A, B and C respectively, most of the subjects in group C expressed complete clearance, there were statistical significant differences between the three studied groups.
- Most of the subjects in group A expressed no pain during treatment (80.0%), there were statistical significant differences between the three studied groups regarding the tolerability of the treatment.
- No serious side effects were reported in patients of our study, there was no
statistical significant difference between the three studied groups.
- Recurrence was found in group A and B more than group C, there were statistical significant differences between the three studied groups.
- Numbers of visits in group B were more than group A and C, there were statistical significant differences between the three studied groups.
- Comparison between the different studied groups regarding satisfaction with treatment showed that, group C shows more satisfaction than other groups at different follow up times.