الفهرس 
Hepatocellular CarcinomaOnly 14 pages are availabe for public view
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Abstract
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The American Cancer Society report of the incidence and prevalence of cancers within the USA states that HCC continues to show the single greatest increase in incidence compared with other cancers. Hepatocellular carcinoma is unique in that it most often occurs against a background of chronic liver disease and cirrhosis. (Wu et al.,2010).
The study was carried out on 20 HCC patients (group I), 20 patients liver cirrhosis (group II ) and 20 normal volunteers (group III). All were recruited from Internal Medicine Department and Hepatology inpatient and outpatient clinic in Ain Shams University Hospitals in the period from (May 2010) to (February 2011).
The aim of this study was to determine lipid profiles in hepatocellular carcinoma (HCC) patients compared to other chronic liver diseases and normal subjects.
All the patients included in our study were subjected to full history taking and clinical examination, laboratory investigation including liver function tests, alpha feto protein, pelviabdominal ultra sound (with special comment on portal vein patency) and spiral triphasic CT.
The current study revealed clearly lower levels of total cholesterol, triglyceride, HDL and LDL among HCC and liver cirrhosis groups compared to control group and the difference is highly significant statistically.
This study concluded that there is inverse correlation between HCC tumor size and (total cholesterol & LDL) levels. On the other hand, there was no significant comparison between the tumor size and (TG & HDL) levels.
Also we concluded that there is a relationship between lipid profile and Child classification in cirrhotic patients. There was significant inverse correlation between TG , HDL levels and child classification. In contrast there was non significant comparison between the 3 groups regarding total cholesterol and LDL levels.