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العنوان
Comparative studies on different Rift Valley Fever attenuated vaccines /
المؤلف
Ibrahim, Alfons Mina.
هيئة الاعداد
باحث / الفونس مينا ابراهيم
مشرف / محمد حسنين عبيد
مناقش / أحمد يس عبد الفتاح محسن
مناقش / فيصل خليل حموده
الموضوع
Rift Valley fever. Infectious diseases.
تاريخ النشر
1996.
عدد الصفحات
165 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/1996
مكان الإجازة
جامعة بنها - كلية الطب البيطري - infectious diseases
الفهرس
Only 14 pages are availabe for public view

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from 165

Abstract

Rift Valley Fever (RVF) is an infectious disease. The mean to control the disease was vaccination and eradication of vector. Many vaccines were used for this purpose, among them were locally prepared attenuated RVF vaccine and imported attenuated RVF vaccine. In this study, trials were conducted
to compare between them
Firstly, titration of original RVF virus vaccines on BHK cell line, the titer was 10’ TCI%0 / ml, 10’ TCIDeo / ml in locally and imported attenuated RVF vaccines respectively. Safety test was conducted by inoculating in hamster 0.5 ml I/P for both vaccines and both vaccines were safe.
Physical examination of vaccinated animals showed slight elevation of body temperature post vaccination with either local or imported RVF vaccine.
The virus was reisolated from serum samples containing from sheep and calves. Ocular, nasal and rectal swabs were obtained from vaccinated animals were free from the virus.
One pregnant ewe vaccinated with locally prepared RVF vaccine (1 ml S/C) was aborted 10 th day after vaccination.
Seroconversion studies using SNT, AGPT and ELISA revealed that the protective level was achieved in the first week post vaccination. Also, these studies recommended the use of local vaccine to control RVF disease.