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Abstract AR is an allergen-induced inflammatory disease of the nasal mucosa. It is the most common IgE- mediate inflammatory disease. It is classified into seasonal and perennial AR. its onset is greatest in adolescence. AR may be influenced by genetic susceptibility, environmental factors and/or exposure to allergens. The allergic response is mediated primarily by type-1 hypersensitivity reaction. The most characteristic symptoms are nasal itching, sneezing, running nose and nasal blockage. Antihistamines and intranasal corticosteroids are the 1st line of treatment. UV phototherapy has a profound immunosuppressive effect so it is used in treatment of atopic dermatitis and AR. Our present study is a systematic review to evaluate the effect of intranasal UV phototherapy on AR cases. The search was done on the MEDLINE database, then screening and evaluation of the articles was done. The most commonly used UV phototherapy is mUV/VIS. The 3 included studies did not give satisfactory results. So we concluded that UV phototherapy is not a reliable method for treatment of AR. |