الفهرس 
HCV BackgroundOnly 14 pages are availabe for public view
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Abstract
Infection with HCV is the most common liver disease in HD
patients, while liver disease is a significant cause of morbidity in
patients with end stage renal disease treated by dialysis or transplantation.
The prevalence of hepatitis C virus (HCV) infection is estimated
to be 2% worldwide, Egypt has the largest epidemic of hepatitis C virus
(HCV) in the world with 14.7% of the population are infected with
HCV.
The prevalence of anti-HCV positivity among dialysis patients
varies in different countries (5%-85% worldwide), but may exceed 95%
in some HD units.
Our study included all ESRD patients undergoing HD in RedSea
governorate. There were 103 patients undergoing HD in RedSea
governorate distributed in 5 HD units. these HD units are in Hurghada
(2 centers),1 in Safaga, 1 in Queser and one center in RasGhareb, 4
units were governmental while only 1 center were private having.
Most of HD patients in RedSea Governorate are males, there was
59, male that represent (57.28%) of all HD patients, and 44 females
(42.72%). The age of the affected patients ranged from 19 to 70 years
In this study, we found that the most common causes of chronic
renal failure were hypertension (20.39%), Diabetes mellitus (8.74%),
unknown (33%), chronic pyelonephritis, Obstructive uropathy,
polycystic kidney (PCK), and Nephrotic Syndrom,cong anomalies.
The total number of –ve HCV patients from the start of their
dialysis is 83 ones. 73 ones of them still free of HCV and 10 ones
converted to positive state through out their duration of HD.
In the present study we searched for the factors associated with
HCV seroconversion, some of these factors were not of a statistically
significant value like; previous blood transfusion, previous surgery
switching between dialysis places , family history of HCV, age and sex.
Other factors like, vascular access, Bilharziasis, were of significant
value.
All patients in the work were evaluated using questionnaire form
for assessment of risk factors causing HCV infection in hemodialysis
patients such as; Age by years, Sex, Duration of hemodialysis by
months, Previous blood transfusion, Previous surgery, Isolation
procedures in the centers, Dialysis in other centers, Vascular access
used, History of Shistosomiasis, History of HBs Ag, Family history of
hepatitis, Cause of chronic kidney disease