الفهرس | Only 14 pages are availabe for public view |
Abstract Schistosomiasis or bilharzia is a tropical parasitic disease caused by blood –dwelling fluke worms of the genus Schistosoma. In the absence of an effective and safe vaccination, chemotherapy continues play a central role in schistosomiasis control. The control of this disease depends almost exclusively on the drug praziquantal, and there are no alternative drugs in sight. Natural compounds have recently attracted significant attention due to their relevance to parasitic infection and potential developmental into new therapeutic agents. Bee products are natural products which were reported to have many biological benefits. Apitherapy is the medical use of honey bee products. This can include the use of honey; pollen; bee bread; propolis; royal jelly and bee venom. The objective of the present work was carried out to investigate the potential effect of honeybee workers (Apis mellifera L.) venom (sting or injection) or proplis on Schistosoma mansoni infected mice on some parasitological; histological; immunological and molecular parameters as the following: 1- Parasitological studies: including determination relative liver and spleen body weight; Worm burden; Oogram pattern and Ova count per gram tissue. 2- Histological studies: including measurement granuloma diameter in liver histology and examination liver histology changes. |