![]() | Only 14 pages are availabe for public view |
Abstract Our ability to tailor the chemical and physical properties of polymers over a wide range of characteristics, the use of polymers is finding a permanent place in sophisticated electronic measuring devices such as sensors. Moreover, conducting polymer-based biosensors are likely to cater to the pressing requirements such as biocompatibility, possibility of in vivo sensing, continuous monitoring of drugs or metabolites, multi-parametric assays, miniaturization and high information density. Detection of danazol using conducting Ppy is one example for using of conductive polymers as a biosensor. This research introduced a simple, sensitive, time saving and reliable method for determination of very low concentrations of danazol. Samples of Ppy doped with DBSA were prepared electrochemically using cyclic voltammetry, normal pulse voltammetry and chronoamperometry. Different preparation conditions were tried and the optimum conditions were found to be 0.1M pyrrole and 0.1M DBSA. Cyclic voltammetry was used in the range from -1 to IV for 30 cycles. Polypyrrole films doped with DBSA were prepared used chronoamperometry technique at potentials 0.6, 0.7, 0.8 and 0.9V over time period 3600s. The effect of potential on polypyrrole film prepared using chronoamperometry was studied. Normal pulse voltammetry was used for preparation at a fixed potential 0.8-IV with sample period 0.5, 1, 1.5 and 2ms, pulse time 0.1, 0.5 and Is and step size 2, 4, 6 and 8 mV. The effect of pulse parameters of step size, sample period and pulse time on deposited film was also studied. FTIR and XRD were applied for studying composition and crystallinty of samples prepared using different techniques. FTIR analysis confirmed the formation of polypyrrole doped with DBSA on the surface of electrodes. However, incorporation of DBSA anions into the electropolymerised polypyrrole varied from weak, in case of films |