الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Renal complications are common in liver cirrhosis, especially in patients with refractory ascites, and they can negatively impact survival. All patients who have advanced cirrhosis should be frequently monitored for renal dysfunction. Serum creatinine is influenced by age, gender, ethnicity muscle mass and protein intake. Formulas including Cockcroft-Gault and MDRD could overestimate the GFR in patients with cirrhosis and should not be used. Finally, creatinine clearance overestimates GFR due to creatinine secretion and requires accurate urine collection, making this impractical in the outpatient setting. Hepatologists should perhaps use novel measures of kidney function and biomarkers, like cystatin C and the cystatin C-based equation for estimated GFR, more frequently, as these have been shown to be superior to creatinine.
Seventy consecutive patients with liver cirrhosis presenting at the Liver Transplantation Unit of the National Liver Institute, Menoufiya University as potential candidates for liver transplantation were prospectively included in this study. Inclusion criteria were patients age less than 80 years and more than 18 years, serum creatinine less than 1.5 mg/dL and absence of dehydration, sepsis and gastrointestinal bleeding one month before enrollment into the study.