الفهرس 
Controlled HypotensionOnly 14 pages are availabe for public view
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Abstract
Controlled hypotension is defined as a reduction of the systolic blood pressure to 80-90 mmHg, a reduction of mean arterial blood pressure (MAP) to 50-65 mmHg or a 30% reduction of baseline MAP.It has been indicated in maxillofacial surgery to reduce bleeding, facilitate surgery and decrease the need for blood transfusions.The ideal agent for inducing controlled hypotension should be easy and safe to use, have a short time of onset, have rapid elimination without toxic metabolites, and have predictable and dose dependant effects.This study was performed on 40 adult patients ASA I &II, aged between 20-60 years in Tanta University hospital from January 2011 to July 2012 to compare the efficacy of intravenously administered dexmedetomidine and sodium nitroprusside in inducing controlled hypotension in patients undergoing elective maxillofacial surgeries. Exclusion criteria included: Patients with clinically significant neurologic,cardiovascular,renal or hepatic diseases, uncontrolled hypertension,patients with pre-existing coagulation defect or on anticoagulant therapy, patients who were pregnant or breast feeding and patients allergic to alpha-2 adrenergic agonists or sodium nitroprusside.Operations less than 2 hours and more than 3
hours were excluded.