الفهرس 
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Abstract
Otitis media is one of the most common infections in childhood. Within the first 3 years of life; up to 80% of children will have experienced at least one episode of otitis media requiring specific treatment. Manipulation of the immune system to provide enhanced protection will probably result in a significant decrease in the incidence of this disease process. Vaccination may play a significant role in this endeavor. As Streptococcus pneumoniae is one of the predominant bacterial pathogens involved in acute otitis media (AOM), pneumococcal vaccines may be effective in preventing or decreasing the burden of disease related to otitis media.There are two types of pneumococcal vaccines:
1. Pneumococcal polysaccharide vaccine contains purified capsular polysaccharide from each of 23 capsular types which is suitable for adults 65 years or over.
2. Pneumococcal conjugate vaccine which is suitable for children under 2 years of age.
The purpose of this meta-analysis study was to answer the following question: is pneumococcal vaccination having a role in prevention of acute otitis media in children?
In our meta-analysis study, 5 studies fulfilled the inclusion criteria 4 of them their data analysed by software revman 5 these studies done on 16603 patients and there was 3925 acute otitis media episodes in control group and 3654 episodes in vaccine group.
The result toward the using pneumococcal vaccination in prevention of acute otitis media was significant and the vaccine efficacy was 5% in prevention of acute otitis media episodes.
The Conclusion that was found from the results of our meta-analysis study and our research that there is evidence that pneumococcal vaccine has arole in prevention of acute otitis media in children.