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Abstract Congenital diaphragmatic hernia (CDH) is a condition that is classically described as a ”failed closure of the pleuroperitoneal canals between the eighth and tenth week of gestation”. This creates an opening between the supraperitoneal cavity and the inferior thoracic wall early in development. The intestine protrudes into the chest cavity and encroaches upon the lungs and heart; leading to pulmonary hypoplasia and pulmonary hypertension. Prenatal diagnosis is key to develop a suitable management plan that includes taking care of the patient at a specialized institution and support by a multidisciplinary team. Advancements in new modalities in the management like prenatal in utero surgery such as fetoscopic tracheal occlusion and postnatal management with gentile ventilation, HFOV, NO, ECMO and liquid ventilation then proceed to surgical correction of the problem by Minimally invasive surgery with thoracoscopic or laproscopic approche have led to improved overall survival of infants who have CDH. Despite these new modalities in the management still there is high morbidity and mortality rate in CDH |