الفهرس 
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Abstract
HCV) infection are at risk of a great number of extrahepatic manifestations (EHMs) up to 40-76% of patients infected with HCV develop at least one EHM during the course of the disease (Cacoub, 2000 and Cacoub, 1999). EHMs may often be the first and only clinical sign of chronic hepatitis C infection. Evidence of HCV infection should always be sought out in cases of non-specific chronic fatigue and/or rheumatic hematological, endocrine or dermatological disorders. The pathogenesis of EHM is still not fully understood, although most studies suggest that the presence of mixed cryoglobulinemia, particular lymphotropism of the virus and non-cryoglobulinemic autoimmune phenomena constitute the major pathogenic factors (Ferri, 2007). Nevertheless, pathogenesis and epidemiology of many EHMs requires further investigation .
The aim of the present study was to evaluate the effect of chronic HCV infection on the micro vascular complications in non diabetic patients . To fulfill this aim 50 patient were studied. They conclude unselected, untreated HCV referral population .
All groups were subjected to the following:
Complete history taking, physical and neurological examination with special attention to peripheral neuropathy, complete blood picture fasting and 2h post-prandial blood glucose ,HbA1C level, liver function.