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Abstract The objective of this study was to compare optical loupe with surgical microscope as regard to sperm retrieval rate (SRR) in microsurgical TESE in cases with NOA. Eighty four patients with non-obstructive azoospermia were subjected to microsurgical testicular sperm extraction (TESE) using optical loupe (8x) for one side. If the initial search at the operation theater was negative for sperm, the other testis was opened using surgical microscope (20 – 32x). In 31 patients, the initial search proved to be positive for sperm and there was no need to open the contralateral testis. In the other 53 patients, TESE using surgical microscope were performed. After prolonged search in the embryology laboratory sperm were found in 10 patients. Three patients were positive for sperm in the loupe side only, two patients were positive in the microscope side only. In the remaining five patients sperm were retrieved from both sides. The overall SRR was 48.8%. In conclusion, the use of optical loupe with magnification 8x can achieve SRR comparable to the surgical microscope during microsurgical TESE in cases of non obstructive azoospermia. |