الفهرس | Only 14 pages are availabe for public view |
Abstract Critically ill patients are immune suppressed, invasively monitored and exposed to aggressive interventions that put them at increased risk of infectious complications while residing in PICU. Fungal pathogens were an increasing important cause of infection among patients in intensive care unit. Mold infections continue to occur predominantly in patients, who were neutropenic, had received a transplant or treated with corticosteroid or cytotoxic agents. Those most at risk were patients who had CVCs, were receiving parentral nutrition and were on broad spectrum antibiotics or required hemdialysis. The challenge for the future in the management of pediatric nosocomial infection includes improving ways to measure nosocomial infection rates in infants and children, investigating new and multiresistant pathogens, controlling antibiotic use, and developing strategies effective for different providers of pediatric care. In the our study, we screened for infection by fungal strains in patients admitted to pediatric intensive care unit in Menoufiya university hospital and for determining the possible associated factors. This study was conducted on 492 critically ill pediatric patient admitted to PICU from July 2010 to July 2011, every patient was examined and sampled at first day of admission,after five days of admission and seven days of admission. All patients were subjected to the following; full history, thorough clinical examination, assessment of pediatric risk of mortality (PRISM)recording laboratory parameters collection of samples and follow up of them to record their fates (either clinical improvement , discharge or death). |