الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Vascular lesions are common in newborns. The majority of vascular lesions are benign and self-limited conditions, although some are signs of systemic disorders or associated with complications. There are two general categories of vascular lesions: benign vascular neoplasms and vascular malformations. Benign vascular neoplasms, such as hemangiomas, are characterized by proliferation of endothelial cells, while vascular malformations have normal endothelial turnover.
Hemangiomas are the most common soft-tissue tumors of infancy, occurring in approximately 5 to 10 % of one-year-old children, Girls are more frequently affected, and it is more common in Caucasian infants. Mulliken and Glowacki defined hemangiomas as vascular tumors with a growth phase, marked by endothelial proliferation and hypercellularity, and an involution phase marked by decrease in cellularity.
Hemangioma tumors can differ considerably in their growth, size, location and depth: most lesions are relatively small (mean size 6 cm2), sporadic, solitary, localized in the skin, and pose only minor clinical problems.
A division of haemangioma into six stages has been suggested, based on parental history, assessment of growth and investigator assessment: nascent, early proliferative, late proliferative, plateau, involution, and abortive.
Most infantile hemangiomas are benign and do not cause any morbidity or mortality. Occasionally, they may impinge on vital structures and interfere with breathing, vision, eating, or hearing. Ulceration of certain areas (eg, diaper area, neck, mucosal surfaces) is not uncommon. Excessive bleeding is infrequent and rarely, if ever, life threatening. In the past, infantile hemangiomas were confused with other vascular neoplasms, particularly kaposiform hemangioendothelioma and tufted angiomas, which can incite a consumptive coagulopathy that may be life threatening.
Hemangiomas can be categorized as localized (or focal), segmental, or multiple. These classifications are useful in predicting risk for complications and the need for treatment. Multiple lesions are usually indicators of visceral involvement (especially brain, liver or gastrointestinal tract). Segmental lesions tend to be large and are frequently associated with complications.
Neither the cause nor the cell of origin of infantile hemangiomas has been definitively elucidated. Theories abound and several lines of evidence support several divergent theories of the cell of origin, including placental tissue, endothelial progenitor cells (EPCs), and mesenchymal stem cells.
The aim of our work was to study the identification of the morphological criteria and distribution of cutaneous vascular lesions and furthermore to identify the precibitating factors for development of cutaneous v