INTRODUCTION AND AIM OF WORK
LITERATURE REVIEW
Solvent Inhalant Abuse
Overview
Classification
Modes of administration
Reasons for use or abuse
Mechanism of action
Toxicokinetics of inhalant abuse
Toxicity of inhalants
Symptoms of inhalant use
Health risks
Sudden sniffing death syndrome (SSDS)
Withdrawal
Inhalant users
Socioeconomic consequences of inhalant abuse
Prevention and treatment
Toluene Abuse
Overview
Effects on motor functions and behavior
Toxicity on various body systems and health effects
Toluene and oxidative stress
Glue Abuse
Glue inhalation and polyneuropathy
Lead blood level after glue inhalation
Neurotoxicity of glue
Useful Links and Websites
METHODS AND MATERIALS
Evaluation of the effect of two concentration levels of glue and toluene on rat’s behavior and spatial memory following single and daily inhalation for 10 days
Method of glue administration
Effect of single and daily glue and toluene inhalation on the CAR behavior in rats
Effect of daily inhalation (30 min/day for 10 days) of glue and toluene on spatial memory using the radial arm maze test
Evaluation of the effect of single and daily inhalation of glue and toluene on some neurotransmitters in rat’s brain
Evaluation of liver and kidney function following single and daily inhalation of glue and toluene
Investigation of the possible histopathological changes in rat’s brain following glue and toluene inhalation
RESULTS
Effect of glue and toluene inhalation on rat’s behavior and spatial memory
Evaluation of the effect of single and daily inhalation of two concentration levels of glue and toluene on some neurotransmitters in rat’s brain
Evaluation of liver and kidney function following single and daily inhalation of glue and toluene
Investigation of the possible histopathological changes in rat’s brain following glue and toluene inhalation
DISCUSSION
SUMMARY AND CONCLUSIONS
REFERENCES
الفهرس 
