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العنوان
The Effect of Soluble Fibre (Plantago OVata Husk) in Dyslipidemic Type 2 Diabetic Patients
المؤلف
Al Musabahi ,Bashayer Abdulmohsen Mohamad
هيئة الاعداد
باحث / Bashayer Abdulmohsen Mohamad Al Musabahi
مشرف / Mohamad Hesham El Gayar
مشرف / Mohamad Ahmad Shaaban
مشرف / Inas Mohamed Sabry
الموضوع
Plantago OVata Husk-
تاريخ النشر
2013
عدد الصفحات
136.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الغدد الصماء والسكري والأيض
تاريخ الإجازة
19/6/2013
مكان الإجازة
جامعة عين شمس - كلية الطب - Endocrinology and Metabolism
الفهرس
Only 14 pages are availabe for public view

from 136

from 136

Abstract

diagnosed with type 2 diabetes and dyslipidemea for 8weeks before and after taking the Soluble fibre (Plantago ovata husk), they will be divided as follows:
-30 patients were given the Soluble, -30 patients were given placebo. -30 patients were not take anything. We found in study group “group I”:
• After 8 weeks, the mean FBG deceased to 7.75±0.59 mmol/L. This change was statistically significant p<0.001.
• After 8 weeks, the mean PPBG deceased to10.01±1.85 mmol/L. This change was statistically significant p < 0.001.
• After 8 weeks, the mean HA1C decreased to 7.06±0.29 %. This change was statistically significant, p < 0.001.
• After 8 weeks, the mean body weight decreased to 84.53±4.47 kg. This change was statistically significant, p < 0.001.
• After 8 weeks, the mean LDLP decreased to 1.31±0.32 mmol/L. This change was statistically significant, where p < 0.001.
• After 8 weeks, the mean HDLP increased to 2.58±0.61 mmol/L. This change was statistically significant, p < 0.023.
• After 8 weeks, the mean cholesterol decreased to 3.36±0.54 mmol/L. This change was statistically significant, p < 0.008.
• After 8 weeks, the mean triglycerides deceased to 1.09±0.44 mmol/L. This change was statistically significant, where p <0.007.
• After 8 weeks, the mean HOMA-IR deceased to 32.38±4.16 mmol/L. This change was statistically significant, p < 0.001.
Psyllium has been studied as a ”non-systemic” cholesterol-lowering agent, with generally modest effects seen on total cholesterol and low-density lipoprotein levels. Several psyllium-containing cereals such as Heartwise® and Bran Buds® have been touted for their potential lipid-lowering and ”heart health promoting” effects (Rockville and Bethesda, 2010).
Po-husk, apart from lowering LDL-C, also has been shown that it reduced TG, TG related to certain gene variants, TC, Apo B-100, oxLDL, insulin-resistance and systolic BP in mild-moderate hypercholesterolaemic individuals (Sola et al., 2010).
The soluble fiber found in psyllium husks plays an important role in lowering cholesterol. Psyllium also softens stool and relieves constipation, irritable bowel syndrome, hemorrhoids, and other intestinal problems. When psyllium husk comes in contact with water, it swells and forms a gelatinous mass that stimulates the transport of waste through the intestinal tract.
Soluble fibers such as those in psyllium husk, and oat bran have a cholesterol-lowering effect when added to a low-fat, low-cholesterol diet. Studies have shown psyllium to be quite effective in lowering total as well as LDL (”bad”) cholesterol levels, which can be helpful to those with high cholesterol (hypercholesterolemia) and those at increased risk for developing hypercholesterolemia, such as people with type 2 diabetes (MDidea, 2010).

Studies suggest that a high-fiber diet, which may include psyllium, can lower insulin and blood sugar levels and improve cholesterol and triglyceride levels in people with diabetes. This type of diet may also help prevent diabetes in those at risk for the condition, also psyllium may enhance the sensation of fullness and reduce hunger cravings. For these reasons, incorporating psyllium and other sources of fiber into the diet may aid weight loss and may help lower blood pressure (MDidea, 2010).