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العنوان
Impact of Neonatal Asphyxia on Stem Cell Viability and the Effect of Cerebrolysin on its Revitalization/
الناشر
Dina Mohamed Akmal،
المؤلف
Dina Mohamed ،Akmal
هيئة الاعداد
باحث / Dina Mohamed ،Akmal
مشرف / Nadia Hassan ،Badrawi.
مشرف / Lamiaa Mohamed ،Mohsen.
مشرف / Hala Gabr ،Metwaly.
تاريخ النشر
2010.
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة القاهرة - كلية الطب - طب الاطفال
الفهرس
Only 14 pages are availabe for public view

from 169

from 169

Abstract

Perinatal fetal distress with subsequent hypoxic ischemic encephalopathy is the leading cause for brain injury and mortality in neonates worldwide. The neuron-regenerative potential of cord blood stem cells has been proven in many experimental animal models. Hypoxia induces mobilization and activation of hemopoietic and mesenchymal stem cells. Umbilical cord is a rich source for mesenchymal stem cells that can be a potential source for autologous transplantation for tissue regeneration. This work is designed to examine the viability, cycling state and neural transdifferentiation potential of cord blood mononuclear cells in hypoxic, normoxic and preterm cord blood.
Key Words: Hypoxia– Stem cells –Neural Transdifferentiation