الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
Diabetes mellitus, a disease that has been reaching epidemic proportions, is an important risk factor to the development of cardiovascular complication. Diabetes causes changes within the cardiac structure and function, even in the absence of ischemic, hypertensive or valvular heart diseases. The left ventricular diastolic dysfunction represents the earliest pre-clinical manifestation of diabetic cardiomyopathy, preceding the systolic dysfunction and being able to evolve to symptomatic heart failure.
The aim of our study was the early detection of diastolic dysfunction in diabetic patients by conventional echocardiography versus Tissue Doppler imaging.
Our study include 40 diabetic patients and 20 healthy control subjects . All subjects were screened using conventional Echocardiographic parameters and TDI .
The study demonstrate that overall prevalence of diastolic dysfunction was 55% in asymptomatic normotensive diabetic subjects which is significantly high as compared to healthy subjects .
In our study traditional echocardiography showed that A wave velocity were significantly higher in diabetic group as compared with control group and also that A
/ E ratio was lower in diabetic group as compared with control group subjects with statistically high significance.
TDI showed that Septal Ea(m)velocity was highly significant lower in diabetic subjects as compared with control persons ,and Ea/Aa (m) & Ea/Aa (L) was significantly lower in diabetic subjects as compared with control persons
Also we found that Within 22 diabetic subjects having diastolic dysfunction, there were one patient detected by conventional echocardiography only , eight patients detected by Tissue Doppler only , thirteen patients detected by both traditional echocardiography and TDI.
This means statistically that tissue Doppler as a tool used in detection of diastolic dysfunction is highly significant more valuable as a diagnostic method even in the subclinical phase than conventional Echocardiography .