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العنوان
STUDIES ON THE CHEMICAL CONSTITUENTS
OF CASSIA SP. AND THEIR ACTIVITIES
AS ANTIOXIDANT AGENTS\
الناشر
Ain Shams university.
المؤلف
Abdel-Lateef ,Ezzat El-Sayed.
هيئة الاعداد
مشرف / Mahfouz M. Abdel-Gawad
مشرف / Mortada M. El- Sayed
مشرف / Maher A. Mahmoud
باحث / Ezzat El-Sayed Abdel-Lateef
الموضوع
CASSIA SP. CHEMICAL CONSTITUENTS.
تاريخ النشر
2011
عدد الصفحات
p.:188
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة عين شمس - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

- Evaluation of the methanolic extracts of seven Cassia species as antioxidant agents using different methods as DPPH, total antioxidant capacity and reducing power assay. The results revealed that the seven methanolic extracts have antioxidant properties whereas the methanol extract of Cassia glauca was the most active.
- The phenolic content of each methanol extract of seven Cassia species was determined. The results exhibited that there is a highly correlation between the total phenolic content and ability of the extract as antioxidant agents. Because of C.glauca has high phenolic content, it showed high antioxidant activity.
- Screening of the seven Cassia species as antimicrobial agents against certain bacterial and fungi species showed there is a correlation between the phenolic content and the ability of the extract as antimicrobial agents.
- Owing to the high antioxidant antimicrobial of the methanolic extract of C. glauca, it was subjected to fractionation and each fraction was tested as antioxidant and antimicrobial agents. The results exhibited that there are a correlation between the phenolic content and the activity of the extract. Ethyl acetate fraction derived from the methanolic extract of C.glauca showed high antioxidant and antimicrobial agents.
- Each fraction derived from the methanolic extract of C.glauca was subjected to chromatographic separation using different techniques and the structure of the isolated compounds were elucidated through chemical and spectroscopic analysis as UV, IR, NMR (1H-NMR, 13C-NMR) and mass spectra.
- from the chloroformic extract, three compounds were isolated and identified using different chromatographic and spectroscopic techniques as Di-(2-ethyl hexyl) phthalate (DEHP) (1), apigenin (2) and luteolin (3).
- Chromatographic isolation of ethyl fraction of C.glauca, led to isolation of pure compounds their structures were identified as quercetin (4), quercetin-3-O-β-D-glucopyranoside (5) and kaempferol-3-O-α-L-rhamnopyranosyl (1→6) β-D-glucopyranoside (6).
- from the butanolic extract derived from methanolic extract of C.glauca. Their structures were identified as D(+)-Pinitol (7), quercetin-3-O-α-L-rhamnopyranosyl (1→6) β-D-glucopyranoside (Rutin) (8) and quercetin-3-O- [(1→2) - α-L-rhmnopyranosyl] [(1→6) - α- L-rhmnopyranosyl] β-D-glucopyranoside (9).