الفهرس | Only 14 pages are availabe for public view |
Abstract Clinical and epidemiological studies as well as animal experiments point to the great importance of trace metals in human medicine. A great number of trace metals are now known to be of vital significance; the accumulation of others has been shown to cause severe intoxication and to pose serious environmental problems (Jacob, 1986) Recent improvement in analytical methods for trace metals measurement allows for increased work to study these elements in association with human diseasesf T,etz , 1983) - Trace metals have been shown to affect vascular and myocardial integrity, arterial . tension and hemostasis. The cardiovascular diseases which have been associated with trace metals are atherosclerosis and to lesser extent cerebrovascular, hypertensbve and myocardial diseases (Jacob, 1986). After myocardial infarction, changes in serum and bulk metals have been observed (Webb et al, 1976). However the precise origin of these changes is unknown. The aim of this work is to study some of the trace metals (magnesium, copper, zinc, iron and manganese) in serum of patients with coronary artery disease, to disclose the role of these metals in the production of coronary events as well as their validity as a cheap diagnostic tests for coronary artery disease. |