الفهرس 
CandidaOnly 14 pages are availabe for public view
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Abstract
Vulvovaginal candidiasis is a common disease, millions of women suffer from Vulvovaginal candidiasis at least one episode during their childbearing period, others have infrequent episodes.
Topical azoles remain the first line of VVC treatment, achieving mycologic and clinical cures with minimal systemic effects in 85% to 90% of episodic infections.
Candida is part of the normal flora of the mucocutaneous membranes. The overall carriage rate of Candida in healthy individuals is 80%, and it can be isolated from the genital tract of about 20% of asymptomatic healthy women of childbearing age.
Evaluation of a patient with symptomatic vaginitis requires a thorough physical examination and medical history. Clinical findings and microscopic assessment must be considered.Physical examination may reveal vulvar erythema and swelling, often with discrete pustulopapular peripheral lesions. The cervix appears normal and the vagina erythematous. The adherence of secretions to the vaginal wall can be assessed during sampling.
In the present study, origanum oil and miconazole nitrate was compared as regard antifungal activities in pregnant women with Vulvovaginal candidiasis.
This study was prospective randomized single blind study was conducted on 60 outpatients clinic pregnant women who complain of vaginal candidal infection in Ain shams university, maternity hospital and Benha teaching hospital in the period starting from October 2007 to March 2008.
Patients were randomly allocated into two groups: Group A: 30 Patients received oil of origanum majorana in the form of vaginal suppositories for 6 days. Group B: 30 Patients received miconazole nitrate in the form of vaginal suppositories for 6 days (gynozol). History and examination was done in the first visit and also cervicovaginal swab was taken for mycological assessment, Patient notified how to take treatment.
In the present study we was found that the mean age in group (A) is 26.33333 and in group (B) is 26.8, so, there is no significance difference as p > 0.05. The mean of gestational age in group (A) is 31.93333 and in group (B) is 33.43333, so, there is significance difference as p < 0.05.
In the second visit history and examination to assess the improvement of symptoms and also cervicovaginal swab was taken to reassess the mycological state and cure rate.
Cure rate of miconazole was 72% and Cure rate of origanum majorana was 59.1%.