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Abstract Non-ablative fractional photothermolysis resurfaces skin surface by punching micro-columns of laser beam energy in a fractional manner rather than a solid laser beam. Thulium targets water content in the epidermis, and is therefore fit to treat all skin types since it does not target melanin. Thulium:glass laser is FDA approved for treating melasma, postinflammatory hyperpigmentation, age spots, solar lentigines, actinic keratosia and vascular dyschromias. Patients require only topical anesthesia with less clinical and social downtime, less painful with less discomfort during treatment sessions. (Key Words: Non-ablative - Fractional photothermolysis - Thulium:glass laser - melasma, post-inflammatory – Hyperpigmentation) |