الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of this work is to detect the expression of eNOS gene in the blood and arterial wall of atherosclerotic occlusive arterial disease patients as well as normal vessels. This study was carried out on the 40 patients who are suffering from atherosclerotic occlusive arterial disease (23 males and 17 females) and 10 patients (10 male) who are had traumatic arterial injuries as control group. The range of age was 7-95 years for all patients, 42-95 years for the diseased group (POAD), 7-36 years for the control group. The results of this study showed there is statistical significance in correlation between the two studied groups as there is decrease in expression of eNOS gene in the diseased group than the control group in both tissue (arterial wall) and blood. Keywords: Atherosclerotic occlusive arterial disease Nitric Oxide (NO) Nitric Oxide Synthase (NOS) Endothelial Nitric Oxide Synthase (eNOS) |