الفهرس | Only 14 pages are availabe for public view |
Abstract This study is a prospective cohort one conducted on 320 apparently healthy adults from Shennera village in Gharbia governorate. It was carried out to study the epidemiology of Chronic Kidney Disease (CKD) in the governorate, to asses prevalence and risk factors of CKD. This study was suggested to identify numbers of apparently healthy persons with reduced kidney function, those with inadequate risk-factor control, and persons with previously unknown and undetected diabetes, hypertension, kidney disease, and kidney disease risk factors. Thus, this study tried to suggest a basis for advocating continued targeted screening of high-risk populations. The mean age of the studied participants was (35.7 years), (50.9%) of them were males while (49.1%) were females. The overall prevalence of CKD was 15.6 %.The prevalence of MA was 14.4 %, low GFR was 7.2 and elevated serum creatinine was in 2.8%. from this study it can be concluded that: The prevalence of CKD across the various age categories shows a significant increasing trend (P = 0.00). No significant differences across the prevalence of CKD with gender (P = 0.750) were noted. The anthropometric measures among CKD group gave a more statistical significant difference as regard BMI, Weight, Waist and Hip circumference and analgesic intake than non CKD group. The prevalence of CKD was more significantly higher than non CKD group regarding hypertension, CVD, DM, Bilhariziasis and smoking. The significant independent predictor variables associated with the presence of CKD in a logistic regression model were diabetes (OR = 9.58,), personal history of CVD (OR = 7.74) and hypertension (OR = 3.98). Family history of renal diseases gave no significant difference between studied groups. Lipid profile, anemia and serum creatinine were higher among people with CKD. Microalbuminuria was significantly higher in CKD group. The prevalence of MA was more significantly higher regarding smoking(P=0.002 OR =2.80) than non MA group. The significant independent predictors variables associated with the presence of MA in a logistic regression model were diabetes (OR = 8.62), personal history of CVD (OR = 7.01) and hypertension (OR = 4.92).The factors associated with the presence of MA in included older age group (P 0.001) and higher serum fasting glucose (P <0.001). MA was also found in patients with higher MAP (P < 0.001).from this study it can be concluded that: • The prevalence of CKD across the various age categories shows a significant increasing trend. • The prevalence of CKD was more significantly higher than non CKD group regarding hypertension, CVD, DM, Bilhariziasis and smoking. • Lipid profile, anemia , serum creatinine and Microalbuminuria were higher among people with CKD. |