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العنوان
Analytical studies on the reaction of some antifungal drugs
المؤلف
Mohamed,Nehad Abdel-Hafeez
هيئة الاعداد
باحث / Nehad Abdel-Hafeez Mohamed
مشرف / Faten Ahmed F. Nour El-Dien
مشرف / Gehad Genidy Mohamed
مشرف / Shaban Mohamed Khalil
الموضوع
the reaction of some antifungal drugs-
تاريخ النشر
2009
عدد الصفحات
167.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Biochemistry
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة القاهرة - كلية العلوم - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 168

from 168

Abstract

spectrophotometric determination of miconazole (MCNZ), tioconazole (TCNZ) and clotrimazole (CLMZ) drugs in pure and pharmaceutical preparations through the ion-pair formation reaction with bromocresol purple (BCP), bromocresol green (BCG) and Eriochrome cyanine R (ECR) reagent is described.
Also Solid state investigation of the metal complexes of MCNZ, TCNZ and CLMZ drugs has been carried out to investigate the coordination behavior of the drugs with different coordination sites, toward some bi and trivalent metal ions like Mn(II), Fe(III), Ni(II), Co(II), Cu(II), Cr (III) and Zn(II).
Key Words: Pharmaceutical preparation; spectrophotometry; miconazole, tioconazole and clotrimazole determination; bromocresol purple, bromocresol green, eriochrome cyanine R, metal complexes, elemental analyses, IR, Thermal analyses, biological activity.