الفهرس 
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Abstract
Neonatal encephalopathy, or a persistently abnormal neurologic examination that includes one or more of the following: altered consciousness, abnormal muscle tone or reflexes, altered respirations, and sometimes seizures in the first postnatal hours to days.Ten percent to 15% of affected infants die during the neonatal period, and 25% to 30% of the survivors will have permanent neurologic damage, typically manifesting as mental retardation, cerebral palsy, and/or epilepsy.A controlled reduction of core body temperature by 2- 3ºC, initiated within 6 hours of birth and continued for 72 hours, followed by slow re-warming, results in a significant reduction in death and neurodisability following hypoxic ischemic encephalopathy (HIE).